jpedmd2026-03-16T16:40:11-05:00March 16th, 2026|

Well, here’s some good news for a change. A new drug, acoziborole, has been approved as a new, single-dose, oral treatment for T.b. gambiense sleeping sickness.  More effective against different disease stages and has a much better side effect profile:
https://www.npr.org/2026/03/16/g-s1-113246/sleeping-sickness-drug-treatment-tsetse-fly
https://dndi.org/research-development/portfolio/acoziborole/

jpedmd2026-01-25T14:28:14-05:00January 25th, 2026|

From Matt Yglesias’ January 20 Slow Boring, Blame Trump for Trump-era immigration excesses:

All of this is terrible. And all of it is Donald Trump and Stephen Miller’s doing (with help from the Supreme Court).

And now ICE has committed yet another brutal, inexcusable murder. R.I.P. Alex Pretti, ICU nurse and model American citizen.  None of this would be happening if we had decent, moral leadership and if ICE was operating in a lawful manner (and perhaps operating in states where there are many more illegal immigrants, rather than ones the petulant president likes to goad).  And the reprehensible lying about what is transpiring – sickening. As the New York Times Editorial Board said today, “The administration is urging Americans to reject the evidence of their eyes and ears. Ms. Noem and Mr. Bovino are lying in defiance of obvious truths. They are lying in the manner of authoritarian regimes that require people to accept lies as a demonstration of power.” I am sad and fear for my country.

• More worthwhile reading:

First, from the NY Times Editorial Board, Trump Is Hiding the Truth About the War in Iran:

“There is a reasonable debate to have about the wisdom of this war. Iran’s murderous government does indeed present a threat — to its own people, to its region and to global stability. Mr. Trump could make a fact-based argument for confronting the regime now, especially to prevent it from menacing its neighbors and, above all, from developing a nuclear weapon. We are skeptical, but we acknowledge that there is a case to be made.

Mr. Trump is not making it. Instead, he has lied about the reasons for the war and about its progress, in an apparent attempt to disguise his poor planning and the war’s questionable basis.”

And also from the Times, a most excellent essay from Phil Klay: Trump Has Made a Fundamental Miscalculation about Iran. It’s definitely worth reading.

• I highly recommend Jamelle Bouie’s latest NYT opinion piece – Is There Method to Trump’s Madness? Excerpt:

“So, again, there is no method to this particular madness. There is no method at all. What there is, instead, is a man with a fourth-rate intellect and a fifth-rate temperament who treats reality as a television show for which he is the cloistered, pampered star. But the world actually exists. Real lives are at stake. And his actions have weight that cannot be easily moved.”

• Jamelle Bouie again sums things up very accurately in his Feb. 25 NYT What Trump Hath Wrought essay. An excerpt:

“What Trump has, a little more than one year into his second term, is a failed presidency: one that has crashed on the rocks of his ambition to supplant constitutional government with that of his will. Yes, he has done a tremendous amount of damage. And yes, he has degraded American democracy to the point that it is on life support.”